# Smoking Cessation and Functional CT Assessment

> **NCT03382106** · PHASE4 · COMPLETED · sponsor: **Eric A. Hoffman** · enrollment: 162 (actual)

## Conditions studied

- Emphysema

## Interventions

- **DRUG:** Sildenafil 20 MG
- **DRUG:** Placebo Oral Tablet
- **DIAGNOSTIC_TEST:** Pulse wave velocity
- **DIAGNOSTIC_TEST:** Carotid artery compliance and stiffness
- **DIAGNOSTIC_TEST:** Pressure wave reflection

## Key facts

- **NCT ID:** NCT03382106
- **Lead sponsor:** Eric A. Hoffman
- **Sponsor class:** OTHER
- **Phase:** PHASE4
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2018-03-19
- **Primary completion:** 2024-09-24
- **Final completion:** 2024-09-24
- **Target enrollment:** 162 (ACTUAL)
- **Last updated:** 2025-02-14

## Collaborators

- [object Object]
- [object Object]

## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT03382106

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT03382106, "Smoking Cessation and Functional CT Assessment". Retrieved via AI Analytics 2026-05-27 from https://api.ai-analytics.org/clinical/NCT03382106. Licensed CC0.

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