# A Study to Assess the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of AZD5718 After Single and Multiple Ascending Dose Administration to Healthy Japanese Men

> **NCT03400488** · PHASE1 · COMPLETED · sponsor: **AstraZeneca** · enrollment: 32 (actual)

## Conditions studied

- Coronary Artery Disease

## Interventions

- **DRUG:** AZD5718 oral suspension
- **OTHER:** Placebo matching AZD5817 oral suspension

## Key facts

- **NCT ID:** NCT03400488
- **Lead sponsor:** AstraZeneca
- **Sponsor class:** INDUSTRY
- **Phase:** PHASE1
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2018-01-16
- **Primary completion:** 2018-06-12
- **Final completion:** 2018-06-12
- **Target enrollment:** 32 (ACTUAL)
- **Last updated:** 2018-06-15


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT03400488

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT03400488, "A Study to Assess the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of AZD5718 After Single and Multiple Ascending Dose Administration to Healthy Japanese Men". Retrieved via AI Analytics 2026-05-24 from https://api.ai-analytics.org/clinical/NCT03400488. Licensed CC0.

---

*[Clinical trials dataset](/datasets/clinical-trials) · CC0 1.0*