# Evaluate the Effects of the Environmental Change in Intestine by Antibiotics on the Pharmacokinetic Characteristics of Simvastatin in Healthy Male Volunteers

> **NCT03403972** · PHASE1 · COMPLETED · sponsor: **Seoul National University Hospital** · enrollment: 6 (actual)

## Conditions studied

- Simvastatin Pharmacokinetics and Gut Microbiome

## Interventions

- **DRUG:** Vancomycin 250Mg Capsule

## Key facts

- **NCT ID:** NCT03403972
- **Lead sponsor:** Seoul National University Hospital
- **Sponsor class:** OTHER
- **Phase:** PHASE1
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2017-12-06
- **Primary completion:** 2018-01-11
- **Final completion:** 2018-01-11
- **Target enrollment:** 6 (ACTUAL)
- **Last updated:** 2018-01-19


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT03403972

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT03403972, "Evaluate the Effects of the Environmental Change in Intestine by Antibiotics on the Pharmacokinetic Characteristics of Simvastatin in Healthy Male Volunteers". Retrieved via AI Analytics 2026-06-14 from https://api.ai-analytics.org/clinical/NCT03403972. Licensed CC0.

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