# The Nicotinic Cholinergic System and Cognitive Aging

> **NCT03408574** · PHASE1 · COMPLETED · sponsor: **University of Vermont** · enrollment: 104 (actual)

## Conditions studied

- Healthy Aging

## Interventions

- **DRUG:** Nicotine patch, oral mecamylamine, placebo

## Key facts

- **NCT ID:** NCT03408574
- **Lead sponsor:** University of Vermont
- **Sponsor class:** OTHER
- **Phase:** PHASE1
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2016-10-01
- **Primary completion:** 2021-12-01
- **Final completion:** 2022-01-31
- **Target enrollment:** 104 (ACTUAL)
- **Last updated:** 2023-05-09

## Collaborators

- [object Object]

## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT03408574

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT03408574, "The Nicotinic Cholinergic System and Cognitive Aging". Retrieved via AI Analytics 2026-05-27 from https://api.ai-analytics.org/clinical/NCT03408574. Licensed CC0.

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*[Clinical trials dataset](/datasets/clinical-trials) · CC0 1.0*