# Topical Fibrinogen-Depleted Human Platelet Lysate in Patients With Dry Eye Secondary to Graft vs. Host Disease

> **NCT03414645** · PHASE1,PHASE2 · COMPLETED · sponsor: **Cambium Bio Limited** · enrollment: 64 (actual)

## Conditions studied

- Dry Eye
- Graft-versus-host-disease
- Ocular Discomfort

## Interventions

- **BIOLOGICAL:** CAM-101 10%
- **BIOLOGICAL:** Vehicle Control
- **BIOLOGICAL:** CAM-101 30%

## Key facts

- **NCT ID:** NCT03414645
- **Lead sponsor:** Cambium Bio Limited
- **Sponsor class:** INDUSTRY
- **Phase:** PHASE1,PHASE2
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2018-05-01
- **Primary completion:** 2019-12-12
- **Final completion:** 2020-02-20
- **Target enrollment:** 64 (ACTUAL)
- **Last updated:** 2021-07-27

## Collaborators

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## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT03414645

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT03414645, "Topical Fibrinogen-Depleted Human Platelet Lysate in Patients With Dry Eye Secondary to Graft vs. Host Disease". Retrieved via AI Analytics 2026-05-30 from https://api.ai-analytics.org/clinical/NCT03414645. Licensed CC0.

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