Neoantigen-based Personalized Vaccine Combined With Immune Checkpoint Blockade Therapy in Patients With Newly Diagnosed, Unmethylated Glioblastoma

NCT03422094 · clinicaltrials.gov ↗

PHASE1

Phase

TERMINATED

Status

3

Enrollment

OTHER

Sponsor class

Stopped Manufacturer changed focus to cell therapy

Conditions

Glioblastoma

Interventions

BIOLOGICAL: NeoVax
BIOLOGICAL: Nivolumab
BIOLOGICAL: Ipilimumab
PROCEDURE: Research blood draw
PROCEDURE: Leukapheresis for research

Sponsor

Washington University School of Medicine

Collaborators

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