First-time-in-Human (FTIH) Study to Evaluate Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Single (in Both Fed and Fasted States) or Repeat Doses of GSK3358699

Stopped The trial was terminated for strategic reasons following the emergence of new data.

Conditions

• Arthritis, Rheumatoid

Interventions

• DRUG: Placebo
• DRUG: GSK3358699
• BIOLOGICAL: GM-CSF
• BIOLOGICAL: LPS
• OTHER: Cantharidin

Sponsor

GlaxoSmithKline