A Safety, Pharmacokinetic and Efficacy Study of NUC-3373 in Combination With Standard Agents Used in Colorectal Cancer Treatment

NCT03428958 · clinicaltrials.gov ↗

PHASE1,PHASE2

Phase

COMPLETED

Status

111

Enrollment

OTHER

Sponsor class

Conditions

Colorectal Cancer
Colorectal Neoplasms
Colorectal Carcinoma
Colorectal Tumors
Neoplasms, Colorectal

Interventions

DRUG: NUC-3373 + leucovorin
DRUG: NUC-3373
DRUG: NUFOX
DRUG: NUFOX + VEGF pathway inhibitor
DRUG: NUFOX + EGFR inhibitor
DRUG: NUFIRI
DRUG: NUFIRI + VEGF pathway inhibitor
DRUG: NUFIRI + EGFR inhibitor
DRUG: NUC-3373 + bevacizumab

Sponsor

NuCana plc