Avelumab, Utomilumab, Rituximab, Ibrutinib, and Combination Chemotherapy in Treating Patients With Relapsed or Refractory Diffuse Large B-Cell Lymphoma or Mantle Cell Lymphoma
Conditions
- Recurrent Diffuse Large B-Cell Lymphoma
- Recurrent Mantle Cell Lymphoma
- Refractory Diffuse Large B-Cell Lymphoma
- Refractory Mantle Cell Lymphoma
- Transformed Follicular Lymphoma to Diffuse Large B-Cell Lymphoma
Interventions
- PROCEDURE: Autologous Hematopoietic Stem Cell Transplantation
- DRUG: Avelumab
- DRUG: Carboplatin
- DRUG: Etoposide Phosphate
- DRUG: Ibrutinib
- DRUG: Ifosfamide
- OTHER: Laboratory Biomarker Analysis
- BIOLOGICAL: Rituximab
- BIOLOGICAL: Utomilumab
Sponsor
City of Hope Medical Center
Collaborators