# Thiamine as a Metabolic Resuscitator After Cardiac Arrest

> **NCT03450707** · PHASE2 · TERMINATED · sponsor: **Michael Donnino** · enrollment: 93 (actual)

## Conditions studied

- Cardiac Arrest

## Interventions

- **DRUG:** Thiamine 500 mg IV
- **OTHER:** Placebo

## Key facts

- **NCT ID:** NCT03450707
- **Lead sponsor:** Michael Donnino
- **Sponsor class:** OTHER
- **Phase:** PHASE2
- **Study type:** INTERVENTIONAL
- **Status:** TERMINATED
- **Start date:** 2018-05-06
- **Primary completion:** 2022-02-19
- **Final completion:** 2022-02-19
- **Target enrollment:** 93 (ACTUAL)
- **Why stopped:** DSMB recommendation based on differing mortality in a subgroup analysis
- **Last updated:** 2023-08-24

## Collaborators

- [object Object]

## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT03450707

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT03450707, "Thiamine as a Metabolic Resuscitator After Cardiac Arrest". Retrieved via AI Analytics 2026-05-26 from https://api.ai-analytics.org/clinical/NCT03450707. Licensed CC0.

---

*[Clinical trials dataset](/datasets/clinical-trials) · CC0 1.0*