# Tinostamustine With or Without Radiation Therapy in Treating Patients With Newly Diagnosed MGMT-Unmethylated Glioblastoma

> **NCT03452930** · PHASE1 · COMPLETED · sponsor: **M.D. Anderson Cancer Center** · enrollment: 5 (actual)

## Conditions studied

- Glioblastoma
- Gliosarcoma
- MGMT-Unmethylated Glioblastoma

## Interventions

- **RADIATION:** Radiation Therapy
- **DRUG:** Tinostamustine

## Key facts

- **NCT ID:** NCT03452930
- **Lead sponsor:** M.D. Anderson Cancer Center
- **Sponsor class:** OTHER
- **Phase:** PHASE1
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2018-08-13
- **Primary completion:** 2024-06-05
- **Final completion:** 2024-06-05
- **Target enrollment:** 5 (ACTUAL)
- **Last updated:** 2025-06-04

## Collaborators

- [object Object]

## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT03452930

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT03452930, "Tinostamustine With or Without Radiation Therapy in Treating Patients With Newly Diagnosed MGMT-Unmethylated Glioblastoma". Retrieved via AI Analytics 2026-05-27 from https://api.ai-analytics.org/clinical/NCT03452930. Licensed CC0.

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*[Clinical trials dataset](/datasets/clinical-trials) · CC0 1.0*