# Impact of Reducing Antihypertensive Treatment on Mortality in Frail Subjects With Low Systolic Blood Pressure (SBP).

> **NCT03453268** · NA · COMPLETED · sponsor: **Assistance Publique - Hôpitaux de Paris** · enrollment: 1048 (actual)

## Conditions studied

- Hypertension

## Interventions

- **OTHER:** STEP DOWN strategy
- **OTHER:** Control

## Key facts

- **NCT ID:** NCT03453268
- **Lead sponsor:** Assistance Publique - Hôpitaux de Paris
- **Sponsor class:** OTHER
- **Phase:** NA
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2018-10-02
- **Primary completion:** 2024-08-15
- **Final completion:** 2024-08-15
- **Target enrollment:** 1048 (ACTUAL)
- **Last updated:** 2025-07-20


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT03453268

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT03453268, "Impact of Reducing Antihypertensive Treatment on Mortality in Frail Subjects With Low Systolic Blood Pressure (SBP).". Retrieved via AI Analytics 2026-05-23 from https://api.ai-analytics.org/clinical/NCT03453268. Licensed CC0.

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