# Indwelling Pleural Catheters With or Without Doxycycline in Treating Patients With Malignant Pleural Effusions

> **NCT03465774** · — · RECRUITING · sponsor: **M.D. Anderson Cancer Center** · enrollment: 208 (estimated)

## Conditions studied

- Pleural Neoplasm

## Interventions

- **DRUG:** Doxycycline
- **DEVICE:** Indwelling Catheter
- **PROCEDURE:** Quality-of-Life Assessment
- **OTHER:** Questionnaire Administration
- **OTHER:** Survey Administration

## Key facts

- **NCT ID:** NCT03465774
- **Lead sponsor:** M.D. Anderson Cancer Center
- **Sponsor class:** OTHER
- **Phase:** —
- **Study type:** OBSERVATIONAL
- **Status:** RECRUITING
- **Start date:** 2018-03-08
- **Primary completion:** 2028-12-01
- **Final completion:** 2028-12-01
- **Target enrollment:** 208 (ESTIMATED)
- **Last updated:** 2026-03-05

## Collaborators

- [object Object]

## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT03465774

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT03465774, "Indwelling Pleural Catheters With or Without Doxycycline in Treating Patients With Malignant Pleural Effusions". Retrieved via AI Analytics 2026-05-24 from https://api.ai-analytics.org/clinical/NCT03465774. Licensed CC0.

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*[Clinical trials dataset](/datasets/clinical-trials) · CC0 1.0*
