# A Trial of Doxycycline vs. Standard Supportive Therapy in Newly-diagnosed Cardiac AL Amyloidosis Patients Undergoing Bortezomib-based Therapy

> **NCT03474458** · PHASE2,PHASE3 · TERMINATED · sponsor: **Fondazione IRCCS Policlinico San Matteo di Pavia** · enrollment: 19 (actual)

## Conditions studied

- Cardiac AL Amyloidosis

## Interventions

- **DRUG:** Doxycycline
- **DRUG:** Standard of care therapy

## Key facts

- **NCT ID:** NCT03474458
- **Lead sponsor:** Fondazione IRCCS Policlinico San Matteo di Pavia
- **Sponsor class:** OTHER
- **Phase:** PHASE2,PHASE3
- **Study type:** INTERVENTIONAL
- **Status:** TERMINATED
- **Start date:** 2019-02-11
- **Primary completion:** 2022-05-30
- **Final completion:** 2022-05-30
- **Target enrollment:** 19 (ACTUAL)
- **Why stopped:** difficulty in recruitment
- **Last updated:** 2024-07-11


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT03474458

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT03474458, "A Trial of Doxycycline vs. Standard Supportive Therapy in Newly-diagnosed Cardiac AL Amyloidosis Patients Undergoing Bortezomib-based Therapy". Retrieved via AI Analytics 2026-05-31 from https://api.ai-analytics.org/clinical/NCT03474458. Licensed CC0.

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