# Comparison of Single Intra-articular Injection of Hyruan-One With Hylan G-F 20 in Knee Osteoarthritis

> **NCT03484091** · PHASE4 · COMPLETED · sponsor: **Thammasat University** · enrollment: 276 (actual)

## Conditions studied

- Knee Osteoarthritis

## Interventions

- **DRUG:** Hyruan-One
- **DRUG:** Hylan G-F 20
- **DRUG:** Normal saline

## Key facts

- **NCT ID:** NCT03484091
- **Lead sponsor:** Thammasat University
- **Sponsor class:** OTHER
- **Phase:** PHASE4
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2018-04-01
- **Primary completion:** 2023-06-27
- **Final completion:** 2023-12-31
- **Target enrollment:** 276 (ACTUAL)
- **Last updated:** 2025-09-22


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT03484091

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT03484091, "Comparison of Single Intra-articular Injection of Hyruan-One With Hylan G-F 20 in Knee Osteoarthritis". Retrieved via AI Analytics 2026-05-25 from https://api.ai-analytics.org/clinical/NCT03484091. Licensed CC0.

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