# The Role of Nicotine Dose and Route of Delivery in Affecting Adoption of E-cigarettes and Reducing Exposure to Toxic Combustion Products

> **NCT03492463** · PHASE2 · COMPLETED · sponsor: **Duke University** · enrollment: 94 (actual)

## Conditions studied

- Nicotine Dependence, Cigarettes

## Interventions

- **DRUG:** Nicotine patch
- **OTHER:** Placebo patch
- **OTHER:** E-cigarettes
- **OTHER:** Non-nicotine e-cigarettes

## Key facts

- **NCT ID:** NCT03492463
- **Lead sponsor:** Duke University
- **Sponsor class:** OTHER
- **Phase:** PHASE2
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2018-08-06
- **Primary completion:** 2021-05-31
- **Final completion:** 2021-05-31
- **Target enrollment:** 94 (ACTUAL)
- **Last updated:** 2023-02-08

## Collaborators

- [object Object]

## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT03492463

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT03492463, "The Role of Nicotine Dose and Route of Delivery in Affecting Adoption of E-cigarettes and Reducing Exposure to Toxic Combustion Products". Retrieved via AI Analytics 2026-08-24 from https://api.ai-analytics.org/clinical/NCT03492463. Licensed CC0.

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