Total Marrow and Lymphoid Irradiation, Fludarabine, and Melphalan Before Donor Stem Cell Transplant in Treating Participants With High-Risk Acute Leukemia or Myelodysplastic Syndrome
Stopped Accrual goal
Conditions
- Acute Lymphoblastic Leukemia
- Acute Lymphoblastic Leukemia in Remission
- Acute Myeloid Leukemia
- Acute Myeloid Leukemia in Remission
- Hematopoietic Cell Transplantation Recipient
- Minimal Residual Disease
- Myelodysplastic Syndrome
- Secondary Acute Myeloid Leukemia
Interventions
- DRUG: Fludarabine
- OTHER: Laboratory Biomarker Analysis
- DRUG: Melphalan
- RADIATION: Total Marrow Irradiation
Sponsor
City of Hope Medical Center
Collaborators