# Synaptic Plasticity and Cognitive Function in RASopathies

> **NCT03504501** · PHASE2 · TERMINATED · sponsor: **Technical University of Munich** · enrollment: 16 (actual)

## Conditions studied

- Impaired Synaptic Plasticity
- Impaired Cognition

## Interventions

- **DRUG:** Lovastatin
- **DRUG:** Lamotrigine

## Key facts

- **NCT ID:** NCT03504501
- **Lead sponsor:** Technical University of Munich
- **Sponsor class:** OTHER
- **Phase:** PHASE2
- **Study type:** INTERVENTIONAL
- **Status:** TERMINATED
- **Start date:** 2019-03-22
- **Primary completion:** 2023-02-09
- **Final completion:** 2023-10-31
- **Target enrollment:** 16 (ACTUAL)
- **Why stopped:** The study has been terminated prematurely due to recruitment difficulties. Current status: recruitment stopped and cleaning of the database is ongoing.
- **Last updated:** 2023-11-30


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT03504501

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT03504501, "Synaptic Plasticity and Cognitive Function in RASopathies". Retrieved via AI Analytics 2026-05-25 from https://api.ai-analytics.org/clinical/NCT03504501. Licensed CC0.

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