# Combined Immunotherapy and Radiosurgery for Metastatic Colorectal Cancer

> **NCT03507699** · PHASE1 · COMPLETED · sponsor: **Sheba Medical Center** · enrollment: 19 (actual)

## Conditions studied

- Colorectal Neoplasms Malignant
- Liver Metastases

## Interventions

- **RADIATION:** Liver radiation therapy
- **DRUG:** Nivolumab Injection [Opdivo]
- **DRUG:** Ipilimumab Injection [Yervoy]
- **DRUG:** CMP-001

## Key facts

- **NCT ID:** NCT03507699
- **Lead sponsor:** Sheba Medical Center
- **Sponsor class:** OTHER_GOV
- **Phase:** PHASE1
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2018-12-15
- **Primary completion:** 2021-08-18
- **Final completion:** 2022-05-25
- **Target enrollment:** 19 (ACTUAL)
- **Last updated:** 2023-04-18

## Collaborators

- [object Object]
- [object Object]

## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT03507699

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT03507699, "Combined Immunotherapy and Radiosurgery for Metastatic Colorectal Cancer". Retrieved via AI Analytics 2026-05-23 from https://api.ai-analytics.org/clinical/NCT03507699. Licensed CC0.

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