# Epacadostat (INCB024360) Added to Preoperative Chemoradiation in Patients With Locally Advanced Rectal Cancer

> **NCT03516708** · PHASE1,PHASE2 · RECRUITING · sponsor: **Washington University School of Medicine** · enrollment: 49 (estimated)

## Conditions studied

- Rectal Cancer

## Interventions

- **DRUG:** Epacadostat
- **RADIATION:** Short-course radiation therapy
- **DRUG:** CAPOX chemotherapy
- **DRUG:** FOLFOX chemotherapy

## Key facts

- **NCT ID:** NCT03516708
- **Lead sponsor:** Washington University School of Medicine
- **Sponsor class:** OTHER
- **Phase:** PHASE1,PHASE2
- **Study type:** INTERVENTIONAL
- **Status:** RECRUITING
- **Start date:** 2020-01-06
- **Primary completion:** 2027-07-15
- **Final completion:** 2030-08-12
- **Target enrollment:** 49 (ESTIMATED)
- **Last updated:** 2026-02-11

## Collaborators

- [object Object]
- [object Object]

## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT03516708

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT03516708, "Epacadostat (INCB024360) Added to Preoperative Chemoradiation in Patients With Locally Advanced Rectal Cancer". Retrieved via AI Analytics 2026-07-16 from https://api.ai-analytics.org/clinical/NCT03516708. Licensed CC0.

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