Low-Intensity Chemotherapy and Blinatumomab in Treating Patients With Philadelphia Chromosome Negative Relapsed or Refractory Acute Lymphoblastic Leukemia

NCT03518112 · clinicaltrials.gov ↗

PHASE2

Phase

TERMINATED

Status

6

Enrollment

OTHER

Sponsor class

Stopped Due to Competing Studies

Conditions

Philadelphia Chromosome Negative
Recurrent B Acute Lymphoblastic Leukemia
Refractory B Acute Lymphoblastic Leukemia

Interventions

BIOLOGICAL: Blinatumomab
DRUG: Cyclophosphamide
DRUG: Cytarabine
DRUG: Dexamethasone
BIOLOGICAL: Filgrastim
OTHER: Laboratory Biomarker Analysis
DRUG: Leucovorin Calcium
DRUG: Mercaptopurine
DRUG: Methotrexate
BIOLOGICAL: Pegfilgrastim
BIOLOGICAL: Rituximab
DRUG: Vincristine Sulfate

Sponsor

M.D. Anderson Cancer Center

Collaborators

[object Object]