# Adjunctive Allogeneic Mesenchymal Stem Cells for Treatment-resistant Bipolar Depression

> **NCT03522545** · PHASE1 · RECRUITING · sponsor: **The University of Texas Health Science Center, Houston** · enrollment: 30 (estimated)

## Conditions studied

- Treatment-resistant Bipolar Depression

## Interventions

- **BIOLOGICAL:** Allogeneic Bone Marrow Derived Multipotent Mesenchymal Stromal Cells (MSCs)
- **BIOLOGICAL:** Placebo

## Key facts

- **NCT ID:** NCT03522545
- **Lead sponsor:** The University of Texas Health Science Center, Houston
- **Sponsor class:** OTHER
- **Phase:** PHASE1
- **Study type:** INTERVENTIONAL
- **Status:** RECRUITING
- **Start date:** 2022-04-20
- **Primary completion:** 2026-12-01
- **Final completion:** 2026-12-01
- **Target enrollment:** 30 (ESTIMATED)
- **Last updated:** 2025-06-22


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT03522545

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT03522545, "Adjunctive Allogeneic Mesenchymal Stem Cells for Treatment-resistant Bipolar Depression". Retrieved via AI Analytics 2026-06-05 from https://api.ai-analytics.org/clinical/NCT03522545. Licensed CC0.

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*[Clinical trials dataset](/datasets/clinical-trials) · CC0 1.0*