# A Study to Investigate the Safety and Efficacy of ZS in Patients With Hyperkalemia.

> **NCT03528681** · PHASE3 · COMPLETED · sponsor: **AstraZeneca** · enrollment: 270 (actual)

## Conditions studied

- Hyperkalemia

## Interventions

- **DRUG:** Sodium Zirconium Cyclosilicate 5g
- **DRUG:** Sodium Zirconium Cyclosilicate 10g
- **DRUG:** Placebo

## Key facts

- **NCT ID:** NCT03528681
- **Lead sponsor:** AstraZeneca
- **Sponsor class:** INDUSTRY
- **Phase:** PHASE3
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2021-05-06
- **Primary completion:** 2022-09-15
- **Final completion:** 2022-09-15
- **Target enrollment:** 270 (ACTUAL)
- **Last updated:** 2025-05-14


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT03528681

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT03528681, "A Study to Investigate the Safety and Efficacy of ZS in Patients With Hyperkalemia.". Retrieved via AI Analytics 2026-06-25 from https://api.ai-analytics.org/clinical/NCT03528681. Licensed CC0.

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*[Clinical trials dataset](/datasets/clinical-trials) · CC0 1.0*