# Mild Hypothermia and Acute Kidney Injury in Liver Transplantation

> **NCT03534141** · NA · TERMINATED · sponsor: **University of California, San Francisco** · enrollment: 175 (actual)

## Conditions studied

- Cirrhosis
- End Stage Liver Disease
- Acute Kidney Injury
- Liver Transplant; Complications
- Chronic Kidney Diseases
- Hepatitis c
- Hepatitis B
- NASH - Nonalcoholic Steatohepatitis
- Alcoholic Cirrhosis
- Hepatocellular Carcinoma

## Interventions

- **DEVICE:** Esophageal cooling/warming device
- **OTHER:** Mild hypothermia
- **OTHER:** Normothermia

## Key facts

- **NCT ID:** NCT03534141
- **Lead sponsor:** University of California, San Francisco
- **Sponsor class:** OTHER
- **Phase:** NA
- **Study type:** INTERVENTIONAL
- **Status:** TERMINATED
- **Start date:** 2018-07-07
- **Primary completion:** 2023-08-17
- **Final completion:** 2023-09-14
- **Target enrollment:** 175 (ACTUAL)
- **Why stopped:** Terminated 9/24/23 at 85% target enrollment due to slow accrual of subjects. The decline in enrollment was attributed to changing surgical demographics (higher MELD, more DCD grafts, and increasing use of Normothermic Perfusion technology).
- **Last updated:** 2025-05-16

## Collaborators

- [object Object]
- [object Object]

## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT03534141

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT03534141, "Mild Hypothermia and Acute Kidney Injury in Liver Transplantation". Retrieved via AI Analytics 2026-06-22 from https://api.ai-analytics.org/clinical/NCT03534141. Licensed CC0.

---

*[Clinical trials dataset](/datasets/clinical-trials) · CC0 1.0*