# Nitrous Oxide For Endoscopic Ablation of Refractory Barrett's Esophagus (NO FEAR-BE)

> **NCT03554356** · NA · ACTIVE_NOT_RECRUITING · sponsor: **University of North Carolina, Chapel Hill** · enrollment: 70 (estimated)

## Conditions studied

- Barrett Esophagus
- Intestinal Metaplasia
- Esophageal Dysplasia

## Interventions

- **DEVICE:** CryoBalloon Focal Ablation System

## Key facts

- **NCT ID:** NCT03554356
- **Lead sponsor:** University of North Carolina, Chapel Hill
- **Sponsor class:** OTHER
- **Phase:** NA
- **Study type:** INTERVENTIONAL
- **Status:** ACTIVE_NOT_RECRUITING
- **Start date:** 2018-09-04
- **Primary completion:** 2026-08
- **Final completion:** 2027-08
- **Target enrollment:** 70 (ESTIMATED)
- **Last updated:** 2026-02-27

## Collaborators

- [object Object]
- [object Object]

## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT03554356

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT03554356, "Nitrous Oxide For Endoscopic Ablation of Refractory Barrett's Esophagus (NO FEAR-BE)". Retrieved via AI Analytics 2026-07-16 from https://api.ai-analytics.org/clinical/NCT03554356. Licensed CC0.

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