# Leucine for Depression Study (L-DEP)

> **NCT03557684** · EARLY_PHASE1 · TERMINATED · sponsor: **University of California, Los Angeles** · enrollment: 59 (actual)

## Conditions studied

- Depression

## Interventions

- **DIETARY_SUPPLEMENT:** leucine
- **OTHER:** PO placebo
- **BIOLOGICAL:** lipopolysaccharide (LPS)
- **OTHER:** IV placebo

## Key facts

- **NCT ID:** NCT03557684
- **Lead sponsor:** University of California, Los Angeles
- **Sponsor class:** OTHER
- **Phase:** EARLY_PHASE1
- **Study type:** INTERVENTIONAL
- **Status:** TERMINATED
- **Start date:** 2018-09-01
- **Primary completion:** 2021-07-31
- **Final completion:** 2021-07-31
- **Target enrollment:** 59 (ACTUAL)
- **Why stopped:** COVID-19
- **Last updated:** 2023-06-08

## Collaborators

- [object Object]

## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT03557684

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT03557684, "Leucine for Depression Study (L-DEP)". Retrieved via AI Analytics 2026-06-02 from https://api.ai-analytics.org/clinical/NCT03557684. Licensed CC0.

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