# Monitoring of Immune and Microbial Reconstitution in (HCT) and Novel Immunotherapies

> **NCT03557749** · — · TERMINATED · sponsor: **Masonic Cancer Center, University of Minnesota** · enrollment: 210 (actual)

## Conditions studied

- Immune and Microbial Reconstitution
- Systemic Viral Infection
- Acute-graft-versus-host Disease
- Chronic Graft-versus-host-disease
- Recurrent Malignancy
- Cytokine Release Syndrome
- Allogenic Related Donors
- Cell Therapy/Immunotherapy Patients

## Interventions

- **DIAGNOSTIC_TEST:** Blood Sample
- **DIAGNOSTIC_TEST:** Stool Sample
- **DIAGNOSTIC_TEST:** Urine Sample
- **DIAGNOSTIC_TEST:** Bronchoalveolar Lavage (BAL) fluid
- **DIAGNOSTIC_TEST:** Gastrointestinal biopsy x 2-4
- **DIAGNOSTIC_TEST:** Skin biopsy
- **DIAGNOSTIC_TEST:** Skin, mouth, and/or ocular swab
- **DIAGNOSTIC_TEST:** Apheresis Product
- **DIAGNOSTIC_TEST:** Final cellular product

## Key facts

- **NCT ID:** NCT03557749
- **Lead sponsor:** Masonic Cancer Center, University of Minnesota
- **Sponsor class:** OTHER
- **Phase:** —
- **Study type:** OBSERVATIONAL
- **Status:** TERMINATED
- **Start date:** 2018-09-21
- **Primary completion:** 2023-06-30
- **Final completion:** 2023-08-15
- **Target enrollment:** 210 (ACTUAL)
- **Why stopped:** Accrual goal met
- **Last updated:** 2023-08-21


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT03557749

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT03557749, "Monitoring of Immune and Microbial Reconstitution in (HCT) and Novel Immunotherapies". Retrieved via AI Analytics 2026-06-03 from https://api.ai-analytics.org/clinical/NCT03557749. Licensed CC0.

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