# PReventing EXtubation FAILure Related to Cough

> **NCT03562000** · NA · TERMINATED · sponsor: **Hospices Civils de Lyon** · enrollment: 57 (actual)

## Conditions studied

- Patients Intubated in ICU Before Extubation

## Interventions

- **DEVICE:** Cough Assistance and Systematic Non-Invasive Ventilation
- **PROCEDURE:** control group using the current gold standard of care after extubation, namely the manual drainage by a physiotherapist and the consensual use of Non-invasive ventilation

## Key facts

- **NCT ID:** NCT03562000
- **Lead sponsor:** Hospices Civils de Lyon
- **Sponsor class:** OTHER
- **Phase:** NA
- **Study type:** INTERVENTIONAL
- **Status:** TERMINATED
- **Start date:** 2020-10-20
- **Primary completion:** 2022-03-16
- **Final completion:** 2022-04-05
- **Target enrollment:** 57 (ACTUAL)
- **Why stopped:** The primary evalution criteria had a so few occurrence that it has been a fundamental obstacle to randomize patient. The use of mecanical aide to cough is more widly employ, creating a second limitation.
- **Last updated:** 2022-05-10


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT03562000

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT03562000, "PReventing EXtubation FAILure Related to Cough". Retrieved via AI Analytics 2026-06-08 from https://api.ai-analytics.org/clinical/NCT03562000. Licensed CC0.

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