# Precision Diagnosis Directing HDACi Chidamide Target Therapy for Adult T-LBL/ALL

> **NCT03564704** · PHASE2,PHASE3 · UNKNOWN · sponsor: **Nanfang Hospital, Southern Medical University** · enrollment: 80 (estimated)

## Conditions studied

- Leukemia
- Leukemia, Acute
- Adult Lymphoblastic Lymphoma
- Leukemia, Lymphoblastic
- Leukemia, T Cell
- Adult Acute Lymphoblastic Leukemia
- Lymphoblastic Lymphoma
- Lymphoblastic Leukemia

## Interventions

- **DRUG:** Dexamethasone
- **DRUG:** vincristine
- **DRUG:** Cyclophosphamide
- **DRUG:** Idarubicin
- **DRUG:** Pegaspargase
- **DRUG:** Adriamycin
- **DRUG:** Methotrexate
- **DRUG:** 6-mercaptopurine.
- **DRUG:** Etoposide
- **DRUG:** Cytarabine
- **PROCEDURE:** Bone marrow aspiration
- **PROCEDURE:** Intrathecal injection
- **RADIATION:** Radiation therapy
- **GENETIC:** NGS
- **PROCEDURE:** allogeneic hematopoietic stem cell transplantation
- **DIAGNOSTIC_TEST:** Flow-MRD
- **DIAGNOSTIC_TEST:** FISH
- **DIAGNOSTIC_TEST:** Flow immunophenotyping
- **DIAGNOSTIC_TEST:** Karyotyping
- **DRUG:** Chidamide

## Key facts

- **NCT ID:** NCT03564704
- **Lead sponsor:** Nanfang Hospital, Southern Medical University
- **Sponsor class:** OTHER
- **Phase:** PHASE2,PHASE3
- **Study type:** INTERVENTIONAL
- **Status:** UNKNOWN
- **Start date:** 2016-02-14
- **Primary completion:** 2021-05-30
- **Final completion:** 2021-05-30
- **Target enrollment:** 80 (ESTIMATED)
- **Last updated:** 2018-06-21


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT03564704

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT03564704, "Precision Diagnosis Directing HDACi Chidamide Target Therapy for Adult T-LBL/ALL". Retrieved via AI Analytics 2026-09-10 from https://api.ai-analytics.org/clinical/NCT03564704. Licensed CC0.

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*[Clinical trials dataset](/datasets/clinical-trials) · CC0 1.0*