Phase I Study to Evaluate a Human Monoclonal Antibody (MAb) 10E8VLS Administered Alone or Concurrently With MAb VRC07-523LS Via Subcutaneous Injection in Healthy Adults

PHASE1

Phase

TERMINATED

Status

Enrollment

NIH

Sponsor class

Stopped Sponsor/PI voluntarily paused and stopped study after observing several Grade 2 and Grade 3 redness local reactogenicity reactions at 10E8VLS injection sites

Conditions

Healthy Adult Immune Response

Interventions

BIOLOGICAL: VRC-HIVMAB095-00-AB (10E8VLS)
BIOLOGICAL: VRC-HIVMAB075-00-AB (VRC07-523LS)

Sponsor

National Institute of Allergy and Infectious Diseases (NIAID)