# Effect of Mannitol 20% Versus Hypertonic Saline 7.5% in Brain Metabolism and Oxygenation

> **NCT03573999** · PHASE4 · COMPLETED · sponsor: **Aristotle University Of Thessaloniki** · enrollment: 54 (actual)

## Conditions studied

- Brain Edema
- Metabolic Disturbance
- Electrolyte and Fluid Balance Conditions

## Interventions

- **DRUG:** Mannitol
- **DRUG:** NaCl 7.5%

## Key facts

- **NCT ID:** NCT03573999
- **Lead sponsor:** Aristotle University Of Thessaloniki
- **Sponsor class:** OTHER
- **Phase:** PHASE4
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2018-06-29
- **Primary completion:** 2019-10-31
- **Final completion:** 2019-12-20
- **Target enrollment:** 54 (ACTUAL)
- **Last updated:** 2021-05-07


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT03573999

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT03573999, "Effect of Mannitol 20% Versus Hypertonic Saline 7.5% in Brain Metabolism and Oxygenation". Retrieved via AI Analytics 2026-07-28 from https://api.ai-analytics.org/clinical/NCT03573999. Licensed CC0.

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