# Effects of Sleep Deprivation and Adrenergic Inhibition on Glymphatic Flow in Humans

> **NCT03576664** · EARLY_PHASE1 · COMPLETED · sponsor: **Gitte Moos Knudsen** · enrollment: 22 (actual)

## Conditions studied

- Sleep Deprivation
- Sleep Wake Disorders
- Sleep

## Interventions

- **DRUG:** Carvedilol 25mg
- **DRUG:** Placebo oral capsule

## Key facts

- **NCT ID:** NCT03576664
- **Lead sponsor:** Gitte Moos Knudsen
- **Sponsor class:** OTHER
- **Phase:** EARLY_PHASE1
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2018-08-28
- **Primary completion:** 2019-09-01
- **Final completion:** 2019-10-01
- **Target enrollment:** 22 (ACTUAL)
- **Last updated:** 2022-11-23

## Collaborators

- [object Object]
- [object Object]

## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT03576664

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT03576664, "Effects of Sleep Deprivation and Adrenergic Inhibition on Glymphatic Flow in Humans". Retrieved via AI Analytics 2026-07-04 from https://api.ai-analytics.org/clinical/NCT03576664. Licensed CC0.

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