# Cryoanalgesia to Prevent Acute and Chronic Pain Following Surgery: A Randomized, Double-Masked, Sham-Controlled Study

> **NCT03578237** · NA · COMPLETED · sponsor: **University of California, San Diego** · enrollment: 99 (actual)

## Conditions studied

- Mastectomy
- Upper Limb Amputation Below Elbow
- Upper Limb Amputation Above Elbow
- Lower Limb Amputation Below Knee
- Lower Limb Amputation Above Knee
- Knee Arthropathy
- Shoulder Arthroplasty
- Rotator Cuff Repair
- Video-Assisted Thoracoscopic Surgery (VATS)
- Skin Grafting

## Interventions

- **DEVICE:** Cryoneurolysis (active)
- **DEVICE:** Sham cryoneurolysis procedure

## Key facts

- **NCT ID:** NCT03578237
- **Lead sponsor:** University of California, San Diego
- **Sponsor class:** OTHER
- **Phase:** NA
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2018-08-25
- **Primary completion:** 2022-01-07
- **Final completion:** 2022-11-25
- **Target enrollment:** 99 (ACTUAL)
- **Last updated:** 2023-02-10

## Collaborators

- [object Object]
- [object Object]

## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT03578237

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT03578237, "Cryoanalgesia to Prevent Acute and Chronic Pain Following Surgery: A Randomized, Double-Masked, Sham-Controlled Study". Retrieved via AI Analytics 2026-06-30 from https://api.ai-analytics.org/clinical/NCT03578237. Licensed CC0.

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