# Short-term Effects of TOLCAPONE on Transthyretin Stability in Subjects With Leptomeningeal TTR Amyloidosis (ATTR)

> **NCT03591757** · EARLY_PHASE1 · COMPLETED · sponsor: **Boston University** · enrollment: 10 (actual)

## Conditions studied

- Transthyretin Amyloidosis
- Amyloidosis, Leptomeningeal, Transthyretin-Related

## Interventions

- **DRUG:** Tolcapone

## Key facts

- **NCT ID:** NCT03591757
- **Lead sponsor:** Boston University
- **Sponsor class:** OTHER
- **Phase:** EARLY_PHASE1
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2018-10-30
- **Primary completion:** 2019-04-26
- **Final completion:** 2019-04-26
- **Target enrollment:** 10 (ACTUAL)
- **Last updated:** 2019-06-14

## Collaborators

- [object Object]

## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT03591757

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT03591757, "Short-term Effects of TOLCAPONE on Transthyretin Stability in Subjects With Leptomeningeal TTR Amyloidosis (ATTR)". Retrieved via AI Analytics 2026-06-08 from https://api.ai-analytics.org/clinical/NCT03591757. Licensed CC0.

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