# Vagus Nerve Stimulation and Stress Reduction Training for Migraine

> **NCT03592329** · NA · COMPLETED · sponsor: **Massachusetts General Hospital** · enrollment: 193 (actual)

## Conditions studied

- Migraine

## Interventions

- **BEHAVIORAL:** Stress Reduction Training A
- **DEVICE:** active tVNS
- **BEHAVIORAL:** Stress Reduction Training B
- **DEVICE:** sham tVNS

## Key facts

- **NCT ID:** NCT03592329
- **Lead sponsor:** Massachusetts General Hospital
- **Sponsor class:** OTHER
- **Phase:** NA
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2019-08-20
- **Primary completion:** 2025-01-14
- **Final completion:** 2025-05-29
- **Target enrollment:** 193 (ACTUAL)
- **Last updated:** 2026-02-25

## Collaborators

- [object Object]
- [object Object]

## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT03592329

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT03592329, "Vagus Nerve Stimulation and Stress Reduction Training for Migraine". Retrieved via AI Analytics 2026-05-29 from https://api.ai-analytics.org/clinical/NCT03592329. Licensed CC0.

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