# Active Surveillance and Chemotherapy Before Surgery in Treating Participants With Stage II-III Rectal Cancer

> **NCT03594630** · EARLY_PHASE1 · RECRUITING · sponsor: **M.D. Anderson Cancer Center** · enrollment: 120 (estimated)

## Conditions studied

- Rectal Adenocarcinoma
- Stage II Rectal Cancer AJCC v8
- Stage IIA Rectal Cancer AJCC v8
- Stage IIB Rectal Cancer AJCC v8
- Stage IIC Rectal Cancer AJCC v8
- Stage III Rectal Cancer AJCC v8
- Stage IIIA Rectal Cancer AJCC v8
- Stage IIIB Rectal Cancer AJCC v8
- Stage IIIC Rectal Cancer AJCC v8

## Interventions

- **DRUG:** Chemotherapy
- **OTHER:** Patient Observation
- **OTHER:** Questionnaire Administration
- **PROCEDURE:** Resection of Rectum

## Key facts

- **NCT ID:** NCT03594630
- **Lead sponsor:** M.D. Anderson Cancer Center
- **Sponsor class:** OTHER
- **Phase:** EARLY_PHASE1
- **Study type:** INTERVENTIONAL
- **Status:** RECRUITING
- **Start date:** 2024-03-13
- **Primary completion:** 2026-10-31
- **Final completion:** 2026-10-31
- **Target enrollment:** 120 (ESTIMATED)
- **Last updated:** 2025-11-06

## Collaborators

- [object Object]

## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT03594630

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT03594630, "Active Surveillance and Chemotherapy Before Surgery in Treating Participants With Stage II-III Rectal Cancer". Retrieved via AI Analytics 2026-05-26 from https://api.ai-analytics.org/clinical/NCT03594630. Licensed CC0.

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