Haplocompatible Transplant Using TCRα/β Depletion Followed by CD45RA-Depleted Donor Lymphocyte Infusions for Severe Combined Immunodeficiency (SCID)

NCT03597594 · clinicaltrials.gov ↗

PHASE1,PHASE2

Phase

ACTIVE_NOT_RECRUITING

Status

4

Enrollment

OTHER

Sponsor class

Conditions

Severe Combined Immunodeficiency

Interventions

DRUG: Anti-thymocyte globulin (rabbit)
DRUG: Busulfan
DRUG: Fludarabine
DRUG: Thiotepa
DEVICE: CliniMACS
OTHER: Donor Lymphocyte Infusion

Sponsor

St. Jude Children's Research Hospital