# Epi Off Versus Epi on Corneal Collagen Cross-linking in Keratoconus Patients

> **NCT03598634** · NA · COMPLETED · sponsor: **University of Molise** · enrollment: 32 (actual)

## Conditions studied

- Keratoconus

## Interventions

- **PROCEDURE:** administration of riboflavin for epi-off cross-linking
- **PROCEDURE:** administration of riboflavin for epi-on cross-linking

## Key facts

- **NCT ID:** NCT03598634
- **Lead sponsor:** University of Molise
- **Sponsor class:** OTHER
- **Phase:** NA
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2014-06-01
- **Primary completion:** 2015-06-30
- **Final completion:** 2017-12-31
- **Target enrollment:** 32 (ACTUAL)
- **Last updated:** 2018-07-26


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT03598634

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT03598634, "Epi Off Versus Epi on Corneal Collagen Cross-linking in Keratoconus Patients". Retrieved via AI Analytics 2026-06-02 from https://api.ai-analytics.org/clinical/NCT03598634. Licensed CC0.

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