# Study of A166 in Patients With Relapsed/Refractory Cancers Expressing HER2 Antigen or Having Amplified HER2 Gene

> **NCT03602079** · PHASE1,PHASE2 · COMPLETED · sponsor: **Klus Pharma Inc.** · enrollment: 49 (actual)

## Conditions studied

- HER2-positive Breast Cancer
- HER2 Gene Mutation
- HER-2 Gene Amplification
- HER2 Positive Gastric Cancer
- Salivary Gland Cancer
- Salivary Gland Tumor
- Salivary Gland Carcinoma
- Salivary Gland Neoplasms
- Lung Cancer
- Colo-rectal Cancer
- Rare Diseases
- Solid Tumor
- Recurrent Gastric Cancer
- Recurrent Colon Cancer
- Recurrent Breast Cancer
- Head and Neck Cancer
- Head and Neck Carcinoma
- Bladder Cancer
- Cervical Cancer
- Liver Cancer
- Bile Duct Cancer
- Urologic Cancer
- Pancreatic Cancer
- Prostate Cancer
- Recurrent Prostate Cancer
- Rectal Cancer
- Recurrent Ovarian Carcinoma
- Recurrent Renal Cell Cancer
- Rectal Cancer Stage II
- Rectal Cancer Stage I
- Rectal Cancer Stage III
- Skin Cancer
- Mouth Cancer
- Lip Cancer Stage I
- Tongue Cancer
- Breast Neoplasm Malignant Primary
- Larynx Cancer
- Tonsil Cancer
- Palate Cancer
- Mucoepidermoid Carcinoma
- Primary Peritoneal Carcinoma
- Mucinous Adenocarcinoma Gastric
- Mucinous Breast Cancer Recurrent
- Cholangiocarcinoma

## Interventions

- **DRUG:** A166

## Key facts

- **NCT ID:** NCT03602079
- **Lead sponsor:** Klus Pharma Inc.
- **Sponsor class:** INDUSTRY
- **Phase:** PHASE1,PHASE2
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2018-07-16
- **Primary completion:** 2022-01-12
- **Final completion:** 2022-01-12
- **Target enrollment:** 49 (ACTUAL)
- **Last updated:** 2023-08-03


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT03602079

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT03602079, "Study of A166 in Patients With Relapsed/Refractory Cancers Expressing HER2 Antigen or Having Amplified HER2 Gene". Retrieved via AI Analytics 2026-05-25 from https://api.ai-analytics.org/clinical/NCT03602079. Licensed CC0.

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