# Study of CAR-T Cells Expressing CD30 and CCR4 for r/r CD30+ HL and CTCL

> **NCT03602157** · PHASE1 · ACTIVE_NOT_RECRUITING · sponsor: **UNC Lineberger Comprehensive Cancer Center** · enrollment: 43 (actual)

## Conditions studied

- Lymphoma
- Immune System Diseases
- Immunoproliferative Disorders
- Lymphatic Diseases
- Lymphoproliferative Disorders
- Neoplasms
- Cutaneous Lymphoma
- Cutaneous Anaplastic Large Cell Lymphoma
- Mycosis Fungoides
- Sezary Syndrome
- Lymphomatoid Papulosis
- Cutaneous T Cell Lymphoma
- Gray Zone Lymphoma

## Interventions

- **BIOLOGICAL:** ATLCAR.CD30.CCR4 cells
- **BIOLOGICAL:** ALTCAR.CD30 cells
- **DRUG:** Bendamustine
- **DRUG:** Fludarabine

## Key facts

- **NCT ID:** NCT03602157
- **Lead sponsor:** UNC Lineberger Comprehensive Cancer Center
- **Sponsor class:** OTHER
- **Phase:** PHASE1
- **Study type:** INTERVENTIONAL
- **Status:** ACTIVE_NOT_RECRUITING
- **Start date:** 2018-12-12
- **Primary completion:** 2025-12-16
- **Final completion:** 2039-11-04
- **Target enrollment:** 43 (ACTUAL)
- **Last updated:** 2026-01-06

## Collaborators

- [object Object]
- [object Object]

## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT03602157

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT03602157, "Study of CAR-T Cells Expressing CD30 and CCR4 for r/r CD30+ HL and CTCL". Retrieved via AI Analytics 2026-05-28 from https://api.ai-analytics.org/clinical/NCT03602157. Licensed CC0.

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