# The ESTxENDS Trial- Substudy on the Effects of Using Electronic Nicotine Delivery Systems (ENDS) on Depression

> **NCT03603340** · NA · COMPLETED · sponsor: **University of Bern** · enrollment: 1246 (actual)

## Conditions studied

- Smoking Cessation
- Depression

## Interventions

- **OTHER:** ENDS (vaporizer/e-cig) and smoking cessation counseling
- **OTHER:** Smoking cessation counseling

## Key facts

- **NCT ID:** NCT03603340
- **Lead sponsor:** University of Bern
- **Sponsor class:** OTHER
- **Phase:** NA
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2018-07-16
- **Primary completion:** 2023-08-31
- **Final completion:** 2023-08-31
- **Target enrollment:** 1246 (ACTUAL)
- **Last updated:** 2023-11-15

## Collaborators

- [object Object]
- [object Object]
- [object Object]
- [object Object]
- [object Object]
- [object Object]
- [object Object]

## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT03603340

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT03603340, "The ESTxENDS Trial- Substudy on the Effects of Using Electronic Nicotine Delivery Systems (ENDS) on Depression". Retrieved via AI Analytics 2026-05-30 from https://api.ai-analytics.org/clinical/NCT03603340. Licensed CC0.

---

*[Clinical trials dataset](/datasets/clinical-trials) · CC0 1.0*
