# A Phase 1b Study of PTC596 in Children With Newly Diagnosed Diffuse Intrinsic Pontine Glioma and High Grade Glioma

> **NCT03605550** · PHASE1 · ACTIVE_NOT_RECRUITING · sponsor: **Nationwide Children's Hospital** · enrollment: 64 (estimated)

## Conditions studied

- High Grade Glioma
- Diffuse Intrinsic Pontine Glioma

## Interventions

- **DRUG:** PTC596
- **RADIATION:** Radiotherapy

## Key facts

- **NCT ID:** NCT03605550
- **Lead sponsor:** Nationwide Children's Hospital
- **Sponsor class:** OTHER
- **Phase:** PHASE1
- **Study type:** INTERVENTIONAL
- **Status:** ACTIVE_NOT_RECRUITING
- **Start date:** 2018-08-01
- **Primary completion:** 2024-03-01
- **Final completion:** 2029-03-01
- **Target enrollment:** 64 (ESTIMATED)
- **Last updated:** 2026-03-27

## Collaborators

- [object Object]

## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT03605550

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT03605550, "A Phase 1b Study of PTC596 in Children With Newly Diagnosed Diffuse Intrinsic Pontine Glioma and High Grade Glioma". Retrieved via AI Analytics 2026-05-24 from https://api.ai-analytics.org/clinical/NCT03605550. Licensed CC0.

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