Donor Stem Cell Transplantation Using α/β+ T-lymphocyte Depleted Grafts From HLA Mismatched Donors

NCT03615105 · clinicaltrials.gov ↗

PHASE2

Phase

TERMINATED

Status

9

Enrollment

OTHER

Sponsor class

Stopped Low accrual

Conditions

Acute Lymphoid Leukemia (ALL)
Acute Myeloid Leukemia (AML)
Chronic Myeloid Leukemia (CML)
Hodgkin Lymphoma
Non-Hodgkin Lymphoma
Chronic Lymphocytic Leukemia

Interventions

RADIATION: Hyperfractionated total body irradiation
DRUG: Thiotepa
DRUG: Cyclophosphamide
DRUG: Busulfan
DRUG: Fludarabine
DRUG: Melphalan
DRUG: Clofarabine
PROCEDURE: HPC(A) stem cell allograft
DRUG: Rituximab
DEVICE: Rabbit antithymocyte globulin

Sponsor

Memorial Sloan Kettering Cancer Center