# A First in Human Study in Healthy Volunteers and in Participants With Frontotemporal Dementia With Granulin (GRN) Mutation

> **NCT03636204** · PHASE1 · COMPLETED · sponsor: **Alector Inc.** · enrollment: 64 (actual)

## Conditions studied

- Healthy
- Frontotemporal Dementia

## Interventions

- **BIOLOGICAL:** AL001
- **OTHER:** Placebo

## Key facts

- **NCT ID:** NCT03636204
- **Lead sponsor:** Alector Inc.
- **Sponsor class:** INDUSTRY
- **Phase:** PHASE1
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2018-09-14
- **Primary completion:** 2019-12-31
- **Final completion:** 2019-12-31
- **Target enrollment:** 64 (ACTUAL)
- **Last updated:** 2020-07-27


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT03636204

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT03636204, "A First in Human Study in Healthy Volunteers and in Participants With Frontotemporal Dementia With Granulin (GRN) Mutation". Retrieved via AI Analytics 2026-06-03 from https://api.ai-analytics.org/clinical/NCT03636204. Licensed CC0.

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