# Paracetamol And Ibuprofen/Indomethacin in Closing Patent Ductus Arteriosus

> **NCT03648437** · PHASE1 · TERMINATED · sponsor: **University of Oulu** · enrollment: 22 (actual)

## Conditions studied

- Patent Ductus Arteriosus

## Interventions

- **DRUG:** Paracetamol 10Mg/mL
- **DRUG:** 0.45% Sodium Chloride
- **DRUG:** Ibuprofen
- **DRUG:** Indomethacin

## Key facts

- **NCT ID:** NCT03648437
- **Lead sponsor:** University of Oulu
- **Sponsor class:** OTHER
- **Phase:** PHASE1
- **Study type:** INTERVENTIONAL
- **Status:** TERMINATED
- **Start date:** 2018-09-03
- **Primary completion:** 2024-10-04
- **Final completion:** 2024-10-04
- **Target enrollment:** 22 (ACTUAL)
- **Why stopped:** The PDA patients have vanished. The last recruitment took place in 2022. In the joint discussion of the principal researchers, it was concluded that PDA patients no longer have to be treated in Finland and the study was terminated.
- **Last updated:** 2024-10-18

## Collaborators

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## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT03648437

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT03648437, "Paracetamol And Ibuprofen/Indomethacin in Closing Patent Ductus Arteriosus". Retrieved via AI Analytics 2026-05-30 from https://api.ai-analytics.org/clinical/NCT03648437. Licensed CC0.

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