# Effectiveness of Silver Diamine Fluoride (SDF) in Arresting Cavitated Caries Lesions

> **NCT03649659** · PHASE3 · TERMINATED · sponsor: **University of Michigan** · enrollment: 830 (actual)

## Conditions studied

- Cavities of Teeth

## Interventions

- **DRUG:** Silver Diamine Fluoride
- **DRUG:** Placebo

## Key facts

- **NCT ID:** NCT03649659
- **Lead sponsor:** University of Michigan
- **Sponsor class:** OTHER
- **Phase:** PHASE3
- **Study type:** INTERVENTIONAL
- **Status:** TERMINATED
- **Start date:** 2018-10-08
- **Primary completion:** 2023-04-11
- **Final completion:** 2023-04-27
- **Target enrollment:** 830 (ACTUAL)
- **Why stopped:** The trial stopped early due to meeting interim analysis early stopping rules. Active participants at the time of the interim analyses results did complete their remaining study visits. No new participants were enrolled.
- **Last updated:** 2025-01-07

## Collaborators

- [object Object]
- [object Object]
- [object Object]

## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT03649659

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT03649659, "Effectiveness of Silver Diamine Fluoride (SDF) in Arresting Cavitated Caries Lesions". Retrieved via AI Analytics 2026-05-24 from https://api.ai-analytics.org/clinical/NCT03649659. Licensed CC0.

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