# Pilon Fracture With Intra-articular Injection of N-Acetylcysteine (Pilon NAC)

> **NCT03652753** · PHASE4 · RECRUITING · sponsor: **University of Missouri-Columbia** · enrollment: 30 (estimated)

## Conditions studied

- Pilon Fracture

## Interventions

- **DRUG:** N-acetylcysteine
- **DRUG:** Saline

## Key facts

- **NCT ID:** NCT03652753
- **Lead sponsor:** University of Missouri-Columbia
- **Sponsor class:** OTHER
- **Phase:** PHASE4
- **Study type:** INTERVENTIONAL
- **Status:** RECRUITING
- **Start date:** 2019-01-01
- **Primary completion:** 2026-12
- **Final completion:** 2026-12
- **Target enrollment:** 30 (ESTIMATED)
- **Last updated:** 2026-04-28


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT03652753

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT03652753, "Pilon Fracture With Intra-articular Injection of N-Acetylcysteine (Pilon NAC)". Retrieved via AI Analytics 2026-06-26 from https://api.ai-analytics.org/clinical/NCT03652753. Licensed CC0.

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*[Clinical trials dataset](/datasets/clinical-trials) · CC0 1.0*