# Disease Modifying Therapies Withdrawal in Inactive Secondary Progressive Multiple Sclerosis Patients Older Than 50 Years (STOP-I-SEP)

> **NCT03653273** · PHASE3 · ACTIVE_NOT_RECRUITING · sponsor: **Rennes University Hospital** · enrollment: 250 (estimated)

## Conditions studied

- Multiple Sclerosis

## Interventions

- **OTHER:** DMT withdrawal
- **DRUG:** DMT continuation

## Key facts

- **NCT ID:** NCT03653273
- **Lead sponsor:** Rennes University Hospital
- **Sponsor class:** OTHER
- **Phase:** PHASE3
- **Study type:** INTERVENTIONAL
- **Status:** ACTIVE_NOT_RECRUITING
- **Start date:** 2019-01-24
- **Primary completion:** 2027-07
- **Final completion:** 2027-07
- **Target enrollment:** 250 (ESTIMATED)
- **Last updated:** 2026-03-30


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT03653273

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT03653273, "Disease Modifying Therapies Withdrawal in Inactive Secondary Progressive Multiple Sclerosis Patients Older Than 50 Years (STOP-I-SEP)". Retrieved via AI Analytics 2026-06-02 from https://api.ai-analytics.org/clinical/NCT03653273. Licensed CC0.

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*[Clinical trials dataset](/datasets/clinical-trials) · CC0 1.0*