# New Periodontitis Treatment Based on Hyaluronic Acid and Melatonin

> **NCT03656484** · PHASE2 · COMPLETED · sponsor: **Concordia Dent Srl** · enrollment: 50 (actual)

## Conditions studied

- Chronic Periodontitis

## Interventions

- **DRUG:** Tetracycline-Metronidazole (TM) group
- **DRUG:** TM-Melatonin-Hyaluronic acid (TM-MHa) group

## Key facts

- **NCT ID:** NCT03656484
- **Lead sponsor:** Concordia Dent Srl
- **Sponsor class:** OTHER
- **Phase:** PHASE2
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2019-01-15
- **Primary completion:** 2019-12-20
- **Final completion:** 2019-12-20
- **Target enrollment:** 50 (ACTUAL)
- **Last updated:** 2020-01-27

## Collaborators

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## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT03656484

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT03656484, "New Periodontitis Treatment Based on Hyaluronic Acid and Melatonin". Retrieved via AI Analytics 2026-06-09 from https://api.ai-analytics.org/clinical/NCT03656484. Licensed CC0.

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