# Effect of Topical Naltrexone Ophthalmic Solution on the Signs and Symptoms of Dry Eye in Diabetic Subjects

> **NCT03660475** · PHASE2 · COMPLETED · sponsor: **Sassani, Joseph S., MD, MHA** · enrollment: 60 (actual)

## Conditions studied

- Dry Eye Disease

## Interventions

- **DRUG:** Naltrexone
- **DRUG:** Placebos

## Key facts

- **NCT ID:** NCT03660475
- **Lead sponsor:** Sassani, Joseph S., MD, MHA
- **Sponsor class:** INDIV
- **Phase:** PHASE2
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2018-07-31
- **Primary completion:** 2018-11-01
- **Final completion:** 2018-11-15
- **Target enrollment:** 60 (ACTUAL)
- **Last updated:** 2022-12-02


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT03660475

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT03660475, "Effect of Topical Naltrexone Ophthalmic Solution on the Signs and Symptoms of Dry Eye in Diabetic Subjects". Retrieved via AI Analytics 2026-06-08 from https://api.ai-analytics.org/clinical/NCT03660475. Licensed CC0.

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